Awake craniotomy. Other disorders of brain in diseases classified elsewhere
Conditions
Interventions
Intervention 1: Intervention group: (dexmedetomidine infusion with a LD of 1 µg/kg/h for 15 minutes and then a MD of 0.2 µg/kg/h). Intervention 2: Control group: (propofol1% infusion with a LD of 250
Sponsors
Tehran University of Medical Sciences
Anesthesiology, critical care and pain management research center
Eligibility
Sex/Gender
All
Age
20 Years to 50 Years
Inclusion criteria
Inclusion criteria: The patient should be a candidate for craniotomy surgery using the sleep-awake-asleep method; The patient does not have a previous craniotomy history; The patient does not have a contraindication for full anesthesia; The patient's age is between 20 and 50 years; The patient does not have a history of allergy to any of the drugs under study.
Exclusion criteria
Exclusion criteria: In addition to craniotomy, the patient needs to perform another surgery at the same time; Pregnancy; Breast feeding; The patient has simultaneously heart, renal or liver failure; Severe obesity (BMI>30 kg/m2);
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain intensity. Timepoint: On 2,6,12,24,48 hours. Method of measurement: VAS scale. | — |
Secondary
| Measure | Time frame |
|---|---|
| Diclofenac suppository dosage required. Timepoint: On 2,6,12,24,48 hours. Method of measurement: Medical record.;The duration of hospitalization until the patient is able to move. Timepoint: The entire length of hospitalization. Method of measurement: Medical record.;Nausea and vomiting. Timepoint: On 2,6,12,24,48 hours. Method of measurement: Patient examination.;Vertigo. Timepoint: On 2,6,12,24,48 hours. Method of measurement: Patient examination. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactShima Baniasad
Tehran University of Medical Sciences
Outcome results
None listed