The effect of intravenous infusion of lidocaine during surgery on pain and nausea-vomiting in Stomach Bypass with Laparascopy

Comparison the effect of intravenous infusion of lidocaine with of 1 mg / kg / h and 2mg/ kg / h on reducing pain and nausea-vomiting after surgery of Stomach Bypass with Laparascopy

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT2015121924754N2

Enrollment

Registered

2015-12-26

Start date

2014-12-22

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Relation between effect of intravenous infusion of lidocaine during and after surgery on pain and nausea-vomiting in Stomach Bypass with Laparascopy.

Interventions

Intervention 1: Intravenous lidocaine infusion at doses of 1 mg /kg/hour. Intervention 2: Intravenous lidocaine infusion at doses of 2 mg /kg/hour.

Treatment - Drugs

Intravenous lidocaine infusion at doses of 1 mg /kg/hour

Intravenous lidocaine infusion at doses of 2 mg /kg/hour

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: patient consent, age greater than 18 and less than 60 years; BMI less than 50; ASA equal to or less than 3; Intraoperative lidocaine infusion time up to 4 hours; no sensitivity to lidocaine; no heart diseases; no liver diseases; no kidney diseases; no psychiatric diseases; Avoiding the use of alcohol and drugs addiction Exclusion criteria: Withdraw from the study; Intraoperative lidocaine infusion time more 4 hours; conversion laparoscopy to laparotomy

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Pain. Timepoint: At zero, half an hour, one and six and twelve and twenty-four hours. Method of measurement: V.A.S.;Nausea-vomiting. Timepoint: At zero, half an hour, one and six and twelve and twenty-four hours. Method of measurement: Asking of patient.;Systolic blood pressure. Timepoint: At time zero, half an hour and one hour after the operation. Method of measurement: Mercury sphygmomanometer.;Diastolic blood pressure. Timepoint: At time zero, half an hour and one hour after the operation. Method of measurement: Mercury sphygmomanometer.;Heart Rate count. Timepoint: At time zero, half an hour and one hour after the operation. Method of measurement: Pulse Rate count.	—

Measure

Time frame

Pain. Timepoint: At zero, half an hour, one and six and twelve and twenty-four hours. Method of measurement: V.A.S.;Nausea-vomiting. Timepoint: At zero, half an hour, one and six and twelve and twenty-four hours. Method of measurement: Asking of patient.;Systolic blood pressure. Timepoint: At time zero, half an hour and one hour after the operation. Method of measurement: Mercury sphygmomanometer.;Diastolic blood pressure. Timepoint: At time zero, half an hour and one hour after the operation. Method of measurement: Mercury sphygmomanometer.;Heart Rate count. Timepoint: At time zero, half an hour and one hour after the operation. Method of measurement: Pulse Rate count.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. AE Abedian

Iran University of Medical Sciences

amir_abedian2001@yahoo.com+98 21 6652 5327

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026