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The effect of pomegranate juice powder on diabetic nephropathy

Double-blind clinical study of the therapeutic effects of pomegranate juice powder on renal damage in diabetic nephropathy.

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT2015121725574N1
Enrollment
40
Registered
2016-05-31
Start date
2016-02-29
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Nephropathy caused by diabetes type 2. Diabetes mellitus With renal complications Diabetic nephropathy (N08.3*)

Interventions

Intervention 1: intervention group:routine treatment+blueberry cap qID,2 months. Intervention 2: control group:routine treatment+placebo cap qID,2 months.
Treatment - Drugs
Placebo
intervention group:routine treatment+blueberry cap qID,2 months
control group:routine treatment+placebo cap qID,2 months

Sponsors

Shiraz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: inclusion criteria: patients 20 to 75 years old receiving reducer blood glucose drug and dietary recommendations for at least 6 month with type II diabetes. That the urine microalbumin and the amount of protein in urine 24 hours higher than normal and receive a fixed dose of either or both ACEI or ARB at least 3 months. Exclusion criteria: certain underlying diseases such as autoimmune diseases or cancer, allergies to plants used in the clinical trial, pregnancy and breastfeeding, dialysis.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
The 24-hour urine protein excretion. Timepoint: Before the intervention, one month after the intervention and after the end of the intervention. Method of measurement: 24-hour urine test.;Urine microalbumin excretion. Timepoint: Before the intervention, one month after the intervention and after the end of the intervention. Method of measurement: urine test.

Secondary

MeasureTime frame
Serum BUN. Timepoint: The beginning and end of the intervention. Method of measurement: blood tests.;Serum Creatinine. Timepoint: The beginning and end of the intervention. Method of measurement: blood tests.;Fasting Blood Sugar. Timepoint: The beginning and end of the intervention. Method of measurement: blood tests.;BMI. Timepoint: The beginning and end of the intervention. Method of measurement: blood tests.;GFR. Timepoint: The beginning and end of the intervention. Method of measurement: blood tests.;HDL. Timepoint: The beginning and end of the intervention. Method of measurement: blood tests.;LDL. Timepoint: The beginning and end of the intervention. Method of measurement: blood tests.;Cholesterol. Timepoint: The beginning and end of the intervention. Method of measurement: blood tests.;TG. Timepoint: The beginning and end of the intervention. Method of measurement: blood tests.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactPouya Faridi

Shiraz University of Medical Sciences

faridip@sums.ac.ir+98 917 314 6562

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026