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Clinical trial of evaluation of microneedling and Trichloroacetic Acid 10% effectiveness versus fractional laser to reduce hyperpigmentation in patients with priorbital dark circles

Evaluation of microneedling and TCA 10% effectiveness versus fractional co2 laser in patients with priorbital dark circles

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT2015121625539N1
Enrollment
46
Registered
2016-01-19
Start date
2015-03-20
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

periorbital hyperpigmentation. -

Interventions

Intervention 1: Intervention group 1 : Cases will be treated with microneedling therapy and use of local 10% trichloroacetic acid solution until frost formation , 3 sessions with a month intervals be
Treatment - Devices
Intervention group 1 : Cases will be treated with microneedling therapy and use of local 10% trichloroacetic acid solution until frost formation , 3 sessions with a month intervals between them. Due
Control group : The control group will be treated with fractional laser 3 sessions with a month intervals between them.

Sponsors

Vice chancellor for research , Iran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
28 Years to 62 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Ages from 28 to 63; Skin typesfrom 2 to 4 exclusion criteria: Absence of fallow up by patients and not satisfied to continue; Complications such as allergy to topical agent

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Preorbital hyperpigmentation. Timepoint: 0, 1 and 2 months during treatment . And 3 and 6 months after treatment. Method of measurement: Intensity of the darkening of the skin around the eyes compared to other areas of the face with visio face device.

Secondary

MeasureTime frame
Satisfaction amount. Timepoint: after completion of treatment. Method of measurement: Comparison of reduction preorbital hyperpigmentation by patient , before and after treatment According to schedule ( score 0 to 10 ).;Response to treatment According to the patient. Timepoint: after completion of treatment. Method of measurement: The percentage and score of the patient to treatment ( 0 to 100% ).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMahba Azizi

Iran University Of Medical Sciences

"Abbaszamanian@yahoo.com" ; "A.zamanian@iums.ac.ir"+98 21 6698

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026