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Effects of N-acetylcysteine on the quality of life, anxiety and antioxidant indexes of patients with cardiovascular disease.

Effects of N-acetylcysteine on the quality of life, anxiety and antioxidant indexes of patients with cardiovascular disease.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2015121425526N1
Enrollment
120
Registered
2016-02-01
Start date
2015-12-22
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: cardiovascular disease. Condition 2: cardiovascular disease. Ischaemic heart diseases Ischaemic heart diseases

Interventions

Intervention 1: Intervention group 1: oral administrations of 600MG N- acetyl cysteine (Avicenna Pharmacy Co.) twice a day for 30 days. Intervention 2: Control group: without drug treatment.
Treatment - Drugs
Intervention group 1: oral administrations of 600MG N- acetyl cysteine (Avicenna Pharmacy Co.) twice a day for 30 days.
Control group: without drug treatment

Sponsors

Lorestan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Criteria 1. patients with acute coronary syndrome, coronary artery disease, the treating physician to confirm the diagnosis reached. 2 people (women and men) aged 65-18 years able to read and write their own. 3. People who have the full consent to participate in research. 4. People who have a history of these-acetylcysteine ??orally, by injection or inhalation during the first months of treatment have not. 5 people without a history of hypersensitivity reactions after taking it approved acetylcysteine 6. The people who received both medications or substances with antioxidant effects as vitamin E, A or vitamin A, E, vitamin C, at least one month before the quake 7. People with a history of anti-anxiety drugs, have. 8 people aged 65-18 years. 9. The lack of disease HCV +, HBSAg +, HIV +, diabetes, kidney disease, 10 of pregnancy Exclusion criteria (1) patients who can not understand the questions or did not have the time and location aware. 2. Patients in the study were dissatisfied. 3. Patients who withdrew during the study. 4. People who do not consume drugs. 5 people who died during the study. 6. Individuals involved in the research program to improve the quality of life or reduce anxiety, such as health promotion, and rehabilitation and so on are. 7 people in the business week by experts and researchers to track the phone call not to participate or not. 8. ejection fraction less than 40% for the echocardiogram

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Quality of life. Timepoint: After and before of the intervention. Method of measurement: MacNew Questionnaire.;Anxiety level. Timepoint: After and before of the intervention. Method of measurement: Spielberger Questionnaire.;Blood antioxidant biomarker indexes. Timepoint: After and before of the intervention. Method of measurement: biochemical assesing.

Secondary

MeasureTime frame
-. Timepoint: -. Method of measurement: -.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHamzehe Najafia

Lorestan University of Medical Sciences

hamzehe_najafy@yahoo.com+98 66 3222 8225

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026