Postoperative Nausea and Vomiting. Unspecified adverse effect of drug or medicament
Conditions
Interventions
Intervention 1: In the control group: normal saline is used alone. All subjects received general anesthesia using midazolam( 0.1mg/kg ) propofol (2– 2.5 mg/kg)for induction and fentanyl 2µ/kg for an
Treatment - Drugs
In the control group: normal saline is used alone. All subjects received general anesthesia using midazolam( 0.1mg/kg ) propofol (2– 2.5 mg/kg)for induction and fentanyl 2µ/kg for analgesia and vola
In the intervention group: a combination of (5% dextrose and normal saline) were used. Infusion controlled by infusion pumps at 125 mL/h IV for 2 hours (250 mL) beginning with the start of surgical cl
Sponsors
Vice Chancellor for research of Mashhad University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria : • Age between 18 and 65 years undergoing orthopedic surgery • ASA class I and II exclusion criteria : • high blood pressure (severe) • liver or kidney disease •coagulopathy • Diabetes • Abnormal blood sugar on the morning of the day of surgery • severe hypotension during surgery that requires intravenous administration of large volumes • Lack of consent to participate in the study have
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Severity of Postoperative Nausea and Vomiting. Timepoint: nausea and vomiting PNOV criteria at 30, 60, 120 minutes and 24 hours after ward admission. Method of measurement: It will be measured based on a verbal descriptive scalewhich is related with a visual analog nausea score. | — |
Secondary
| Measure | Time frame |
|---|---|
| Recovery time. Timepoint: based on the time of patients' recovery time it will be different. Method of measurement: The time it takes after the surgery to the patient's recovery (in terms of minutes or hours). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactFarzaneh Fazeli
Mashhad University of Medical Sciences
Outcome results
None listed