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The effect of adding dexmedetomidine to bupivacaine in paravertebral block.

The evaluation of effect of adding dexmedetomidine to bupivacaine on the block in laparotomy surgery

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
IRCT
Registry ID
IRCT2015121212642N23
Enrollment
42
Registered
2015-12-27
Start date
2015-03-30
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

nerve Block. adverse of therapeutic use

Interventions

Intervention 1: In the first group (intervention group) after general anesthesia and completion of the operation, the block identified by ultrasound and bupivacaine 0.25% with a volume of 20 cc with a
Treatment - Other
In the first group (intervention group) after general anesthesia and completion of the operation, the block identified by ultrasound and bupivacaine 0.25% with a volume of 20 cc with a dose of 100 mic
In the second group (control group) after general anesthesia and completion of the operation, the block identified by ultrasound and bupivacaine 0.25% with a volume of 20 cc without dexmedetomidine is

Sponsors

Vice chancellor for research, Iran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 65 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: ASA I-III; there is no known sensitivity or contraindications for injection of studied drugs; non-prescription tranquilizer in the 24 hours prior to anesthesia; no history of chronic use of opioids or benzodiazepines; no history of liver disease; no history of cardiovascular disease; no history of lung disease; lack the urgency of the surgery.Exclusion criteria: Those who find complicated surgery for any reason; intraoperative hemodynamic disturbances; disturbances in consciousness in the post-operative stage; need to continue mechanical ventilation after the end of anesthesia; complications related to surgery.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Amount of narcotic of injection. Timepoint: In times of 2, 6, 12, 24 and 48 hours after surgery. Method of measurement: The based on question of the floor nurses and based on milligram.;Amount of pain. Timepoint: In times of 2, 6, 12, 24 and 48 hours after surgery. Method of measurement: Based on patient state and show the related shaped VAS ruler.

Secondary

MeasureTime frame
Amount of Satisfaction. Timepoint: In times of 2, 6, 12, 24 and 48 hours after surgery. Method of measurement: According to the questionnaire, as excellent, good, average, unhappy.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFarnad Imani

Anesthesiology group of Iran University of Medical Science

Farimani@iums.ac.ir+98 21 6651 5001

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026