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Efficacy of retinoic acid5% cream with microdermabrasion in treatment of photoaging

Comparison efficacy of retinoids acid 5% with microdermabrasion and microdermabrasion with placebo in treatment of photoaging

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT2015121112782N8
Enrollment
90
Registered
2016-02-07
Start date
2014-02-21
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Photoaging. Atrophic disorder of skin, unspecified

Interventions

Intervention 1: Right side of the face is treated with microderm abrasion and retinoic acid 5% peeling. At first, the face is cleaned by aceton, then is treated with microdermabrasion with 70 mmHg. Th
Treatment - Devices
Right side of the face is treated with microderm abrasion and retinoic acid 5% peeling. At first, the face is cleaned by aceton, then is treated with microdermabrasion with 70 mmHg. This device is wor
Left side of the face is treated with microdermabrasion and placebo. At first, the face is cleaned by aceton, then is treated with microdermabrasion with 70 mmHg. This device is work by use of aluminu

Sponsors

Vice chancellor of Isfahan university of medical sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
35 Years to 70 Years

Inclusion criteria

Inclusion criteria: A- Inclusion criteria: patient informed consent for participation, no sensitivity to retinoic acid compounds, no treating for photoaging for at list three months before participation in study.B- exclusion criteria: no using drug regularly or no referring regularly for microderm abrasion, patient discontinuing intervention, using other treatment modality within study

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Photoaging lesions. Timepoint: Baseline, two weeks, one month? two month and four months after start of treatment. Method of measurement: Gloagu grading system.

Secondary

MeasureTime frame
Side effect of treatment with microdermabrasion and retinoic acid 5% peeling. Timepoint: Two week, one month, two month and four month after start of treatment. Method of measurement: Visional clinical evaluation.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Saghi fatemi tabaei

Isfahan university of medical sciences

Mehrabi@med.mui.ac.ir+98 31366855555

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 27, 2026