The effects of L-carnitine in patients with esophageal cancer

Examine the effects of early nutrition rich in L-carnitine on the complication of esophageal cancer

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2015121022840N1

Enrollment

Registered

2015-12-10

Start date

2015-02-20

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Esophageal cancer. Oesophagus, unspecified

Interventions

Intervention 1: Intervention group: in first postoprative day 3 gr L-carnitine in 3 divided doses with every meal diet for 10 days is given . Intervention 2: Control group: in first postopreative

Treatment - Drugs

Intervention group: in first postoprative day 3 gr L-carnitine in 3 divided doses with every meal diet for 10 days is given .

Control group: in first postopreative day a diet without carnitine (diet hospital) will be given in three meals for 10 days .

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Inclusion criteria: patients undergoing esophageal cancer surgery & More than 10 days hospital stay . exclusion criteria : a history of seizure ?bleeding disorders? liver and kidney disease?pregnancy? history of uncontrolled high blood pressure; uncontrolled diabetes; death during the study

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Early complications after surgery for esophageal cancer. Timepoint: 10 days after the start of the study. Method of measurement: Clinical examination and questioning of the patient and clinical records and the preparation and completion of the Chech list.;Nitrogen balance. Timepoint: Before surgry and 10 days After starting the diet. Method of measurement: To determine the nitrogen balance at the same time the amount and type of food that has been recorded in 24 hours, and a 24-hour urine is collected.;Cell blood counting. Timepoint: Before surgery and 10 days after starting diet. Method of measurement: Patient blood samples are taken and sent to the laboratory and by cell counter device to be counted.;BUN,Cr. Timepoint: Before surgery and 10 days after starting diet. Method of measurement: Biochemical analysis of blood samples.	—

Measure

Time frame

Early complications after surgery for esophageal cancer. Timepoint: 10 days after the start of the study. Method of measurement: Clinical examination and questioning of the patient and clinical records and the preparation and completion of the Chech list.;Nitrogen balance. Timepoint: Before surgry and 10 days After starting the diet. Method of measurement: To determine the nitrogen balance at the same time the amount and type of food that has been recorded in 24 hours, and a 24-hour urine is collected.;Cell blood counting. Timepoint: Before surgery and 10 days after starting diet. Method of measurement: Patient blood samples are taken and sent to the laboratory and by cell counter device to be counted.;BUN,Cr. Timepoint: Before surgery and 10 days after starting diet. Method of measurement: Biochemical analysis of blood samples.

—

Secondary

Measure	Time frame
Time unit. Timepoint: After discharge from the hospital. Method of measurement: The patient's clinical records.;Length of stay in icu. Timepoint: Regitrtion after icu. Method of measurement: The patient's clinical records.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAli ne'mati

Ardabil University of Medical Sciences and Health Services

a.nemati@arums.ac.ir+98 4521133510052

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026