Prophylaxis of urinary tract infection(UTI)

Comparison of the effects of co-trimoxazole and co-trimoxazole plus ciprofloxacin in urinary tract infection prophylaxis in kidney transplant patients

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT2015120823743N1

Enrollment

Registered

2015-12-23

Start date

2014-08-22

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Urinary tract infection. Other infectious diseases

Interventions

Intervention 1: Intervention group 1:In Group I, co-trimoxazole was administered with a daily dose of 160/800 mg for a period of six months as in standard protocol. (company Rose daroo). Intervention

Treatment - Drugs

Intervention group 1:In Group I, co-trimoxazole was administered with a daily dose of 160/800 mg for a period of six months as in standard protocol. (company Rose daroo)

Intervention group 2: In Group II, co-trimoxazole was administered daily for six months along with 250 mg ciprofloxacin every 12 hours for the first one month. Cotrimoxazole from Rose daroo company an

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Inclusion criteria: Age over 18 years; Consent to inclusion; The recipient of kidney transplant; Lack of recent urinary infection; Lack of Glucose 6 Phosphate Dehydrogenase(G6PD); No prior consumption of antibiotic. Exclusion criteria: Inaccessibility to the patient to determine various causes of urinary infection such as death or migration; Concurrent use of other antibiotics in the course of investigation; Withdrawal from the study; Allergic reaction to medications; Drug intolerance.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
-. Timepoint: -. Method of measurement: -.;-. Timepoint: -. Method of measurement: -.;Urinary tract infection. Timepoint: 1,3and 6 months after intervention. Method of measurement: Questionnaire, urine analysis and urine culture.;The time of developing urinary tract infection after kidney transplant. Timepoint: 1,3 and 6 months after intervention. Method of measurement: Questionnaire, urine analysis and urine culture.	—

Measure

Time frame

-. Timepoint: -. Method of measurement: -.;-. Timepoint: -. Method of measurement: -.;Urinary tract infection. Timepoint: 1,3and 6 months after intervention. Method of measurement: Questionnaire, urine analysis and urine culture.;The time of developing urinary tract infection after kidney transplant. Timepoint: 1,3 and 6 months after intervention. Method of measurement: Questionnaire, urine analysis and urine culture.

—

Secondary

Measure	Time frame
-. Timepoint: -. Method of measurement: -.;-. Timepoint: -. Method of measurement: -.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAtousa Hakamifard

Isfahan University of Medical Sciences

Atousa_medline@yahoo.com+98 31 3233 4553

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026