Premature rupture of membranes, labour delayed by therapy. Premature rupture of membranes, labour delayed by therapy
Conditions
Interventions
Intervention 1: Intervention group : progesterone ( 400 mg a daily intravaginal. Intervention 2: Control group: routine treatment includes injections of betamethasone 12 mg of progesterone administere
Treatment - Drugs
Intervention group : progesterone ( 400 mg a daily intravaginal
Control group: routine treatment includes injections of betamethasone 12 mg of progesterone administered every 12 hours
Sponsors
Vice Chancellor for Research and Technology University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
15 Years to 48 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: pregnant women with gestational age between 26 to 32 weeks with premature rupture of membranes (PROM); signing informed consent. Exclusion criteria: fetal abnormalities; genetic abnormalities that can affect fetal growth that have been checked by ultrasound at 18 to 20 weeks and 28 to 32 weeks. Along with trisomy screening marker with double or quad marker; precambrian patients; chronic high blood pressure; overt diabetes; pregnancy-related diabetes; detachment; prolapsed umbilical cord; chorioamnionitis; gestational age over 32 weeks (because there isn’t sufficient time to study the effects of progesterone); patient who have had a rupture of the membranes after 36 hours; patient who are in active phase.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Lengthening the interval between the pre-term delivery runny. Timepoint: Daily. Method of measurement: Physical examination. | — |
Secondary
| Measure | Time frame |
|---|---|
| Improving Perinatal Outcomes. Timepoint: Follow baby daily until discharge. Method of measurement: Physical examination. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr.Simin Taghavi
Tabriz University of medical Sciences
Outcome results
None listed