comparison of the effect of three types of orthodontic wires on salivary nickel changes in orthodontic patients

comparison of the effect of NiTi , copper NiTi and epoxy coated NiTi wires on salivary nickel changes in orthodontic patients with metal injection molding brackets

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT2015120725408N1

Enrollment

Registered

2016-02-03

Start date

2016-02-20

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Malocclusion. malocclusion,unspecified

Interventions

Intervention 1: Control group: Metal injection molding(MIM) bracket + nickel-titanium (NiTi) wire. Intervention 2: Intervention group: Metal injection molding(MIM) bracket + Copper nickel-titanium wi

Control group: Metal injection molding(MIM) bracket + nickel-titanium (NiTi) wire

Intervention group: Metal injection molding(MIM) bracket + Copper nickel-titanium wire

Intervention group: Metal injection molding(MIM) bracket + Epoxy coated nickel titanium wire

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Inclusion criteria: All of the patients should needed fixed orthodontic treatment; They should not have intra oral crown and amalgam restoration; Should not smoke, drink alcohol and use special drug; Should not have systemic disease and special dietry; They should be inclined to long term cooperation. Exclusion criteria: Disinclination to continue cooperation; Have done any intra oral metal restoration; Have used alcohol or cigarette.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Nickel ion releasing. Timepoint: Before intervention ; 2 months after intervention. Method of measurement: Measure: Microgram/Milliliter by atomic absorption spectrometry machine.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactOzra Niknam

Jundishapur University of Medical Sciences, Faculty of Dentitry

niknam.o@ajums.ac.ir; ozra.niknam@gmail.com+98 61 3336 7543

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026