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treatment of ataxia in patients with acute peripheral vertigo.

Comparison of diazepam and promethazine in relieving ataxia in patients with acute peripheral vertigo, a clinical trial

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT2015120722777N2
Enrollment
70
Registered
2015-12-26
Start date
2014-08-28
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute peripheral vertigo. Benign paroxysmal vertigo

Interventions

Intervention 1: Intervention 1: Patients with acute peripheral vertigo enroll to the study considering inclusion and exclusion criteria. First arm, include 35 patients who receive 5 mg of intravenous
Treatment - Drugs
Intervention 1: Patients with acute peripheral vertigo enroll to the study considering inclusion and exclusion criteria. First arm, include 35 patients who receive 5 mg of intravenous diazepam. The p
Intervention 2: Patients with acute peripheral vertigo enroll to the study considering inclusion and exclusion criteria. First arm, include 35 patients who receive 12.5 mg of intramuscular promethaz

Sponsors

Vice chancellor for research,Arak University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: aged between 18-60 years old; acute peripheral vertigo and ataxia. exclusion criteria: history of syncope or cardiac event; considerations of a central origin for vertigo; focal neurological deficits; known pregnancy; evidence of drug-induced vertigo or orthostatic hypotension; known dystonic or adverse reaction to diazepam and promethazine or other similar agents; report of taking medication within 24 hours of ED presentation that might affect the results (e.g., antihistamines, antipsychotics, opioid analgesics or sedatives).

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Ataxia. Timepoint: 60 and 120 minutes after intervention. Method of measurement: Romberg Test and tandem gait test.

Secondary

MeasureTime frame
Blood pressure. Timepoint: 60 and 120 minutes after intervention. Method of measurement: Sphygmomanometer.;Heart Rate. Timepoint: 60 and 120 minutes after intervention. Method of measurement: Pulse oximetry.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMaryam Vakili

Arak University of Medical Sciences

maryam.vakili.md@gmail.comabdolghader.pakniyat@gmail.com+98 86 3417 3601

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026