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A comparative study of the effect of vaginal and pessary progesterone along with the vaginal progesterone in preventing preterm delivery in twin pregnancies of pregnant women

A comparative study of the effect of vaginal and pessary progesterone along with the vaginal progesterone in preventing preterm delivery in twin pregnancies of pregnant women

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
IRCT
Registry ID
IRCT20151207025420N2
Enrollment
100
Registered
2024-08-03
Start date
2024-07-22
Completion date
Unknown
Last updated
2024-08-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

preterm Delivery. Sequelae of complication of pregnancy, childbirth, and the puerperium

Interventions

Intervention 1: Pregnant mothers with twin pregnany who have short cervix length in sonography were included in the study and randomly divided into two groups. In one group only vaginal progesterone s

Sponsors

Iran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: Twin pregnancies Pregnancy age 16-18 weeks The cervical length less than 25 mm

Exclusion criteria

Exclusion criteria: Twin-Twin Transfusion Syndrome monoamniotic twins Rupture of the membranes The presence of a major or chromosomal abnormality in at least one fetus Women who have cervical cerclage in their current pregnancy Placenta Previa Progesterone treatment before inclusion Progesterone sensitivity Severe liver defect Porphyria Otosclerosis Major depression Taking drugs that interfere with the effect of progesterone

Design outcomes

Primary

MeasureTime frame
The primary outcome of this study is gestational age at delivery time. Timepoint: gestational age between 16-18. Method of measurement: gestational age(week).

Secondary

MeasureTime frame
Apgar score. Timepoint: After delivery. Method of measurement: apgar score.;Weight. Timepoint: after delivery. Method of measurement: weight.;NICU addmition. Timepoint: after delivery. Method of measurement: day.;Respiratory distress. Timepoint: after delivery. Method of measurement: respiratory symptoms and chest x ray.;ICH. Timepoint: after delivery. Method of measurement: brain ultrasonography.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactNeda Hashemi

Iran University of Medical Sciences

nedahashemi1363@yahoo.com09821 66509283

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026