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Efficacy of transcranial direct current stimulation in reduction of anxiety and crystalline heroin craving.

The efficacy of transcranial direct current stimulation of dorsolateral prefrontal cortex on modulation of anxiety and craving in crystalline heroin dependents in MMT program.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2015120625384N1
Enrollment
40
Registered
2016-01-24
Start date
2015-12-22
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Crystalline Heroin Dependence. Mental and behavioural disorders due to use of opioids

Interventions

Intervention 1: Direct current will be delivered from a constant current stimulator (ActivaDose), and will be transferred by a pair of (35 cm2) electrodes with stimulation intensity of 2mA. Electrode
Treatment - Devices
Direct current will be delivered from a constant current stimulator (ActivaDose), and will be transferred by a pair of (35 cm2) electrodes with stimulation intensity of 2mA. Electrodes are standard c

Sponsors

Behjoo Brain Center
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
25 Years to 50 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: 25 to 50 year-old; right handed male; crystalline heroin smokers, with a history of at least 12 and at most 24 months of crystalline heroin dependence based on DSM-V criteria. Subjects at least have five years education, and are able to read, and understand the questions. Accept and sign the consent form. Exclusion criteria: any current or past major clinical neurologic disorders; central nervous system-effective medication intake; history of epilepsy; brain surgery; brain tumor; intracranial metal implantation; clinically significant head trauma, or any major clinical psychiatric disorders (in axis I, except substance-related disorders).

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Anxiety. Timepoint: Before and after stimulation. Method of measurement: Hamilton Anxiety Scale.;Instant craving. Timepoint: Before and after stimulation. Method of measurement: Drug Desire Questionnair.

Secondary

MeasureTime frame
TDCS side effects. Timepoint: After stimulation. Method of measurement: tDCS side effects check list.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactPeyman Hassani Abharian

Behjoo Brain Center

behjoobraincenter@gmail.com abharian1972@yahoo.com+98 21 4429 3384

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026