Evaluation of intrathecal dexmedetomidine effect on block characteristics during spinal anesthesia for cesarean section

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT201512051766N8

Enrollment

Registered

2016-01-20

Start date

2015-05-22

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

spinal anesthesia. O29.8

Interventions

Intervention 1: Intervention : 12.5 Mg bupivacaine 0.5% plus 5 mic dexmeditomidine (total volume 3 Ml by adding distilled water). Intervention 2: Control : 12.5 Mg bupivacaine 0.5% plus 0.5 Ml 0.9% no

Treatment - Drugs

Placebo

Intervention : 12.5 Mg bupivacaine 0.5% plus 5 mic dexmeditomidine (total volume 3 Ml by adding distilled water)

Control : 12.5 Mg bupivacaine 0.5% plus 0.5 Ml 0.9% normal saline (total volume 3 Ml)

Eligibility

Sex/Gender

Female

Age

18 Years to 45 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria : American Society of Anesthesiologist Physical status 1 or 2 Exclusion criteria : Any absolute or relative contraindication for spinal anesthesia ; BMI > 25 ; history of taking a2 antagonist drugs ; history of hypertension or antihypertensive drug taking ; history of heart disease (ischemic ,valular ,blocks) ; renal failure ; hepatic disease ; history of allergy to study drugs ; inadequate spinal block level

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Peak of sensory block. Timepoint: every 15 min until reaching equal result inthree consecutive session. Method of measurement: using Cotton alcohol method in midclavicular line from distal to proximal of body.;Needing time to reach the peak of sensory block. Timepoint: every 2 min until reaching equal result in three consecutive session. Method of measurement: using Cotton alcohol method in midclavicular line from distal to proximal of body.;Needing time to reach motor block to highest degree. Timepoint: every 15 min. Method of measurement: modified bromage scale.;Time of regression of sensory block. Timepoint: every 15 min in post anesthesia care unit. Method of measurement: time need to regression of sensory block to level of S1 using.;Time need to regression of motor block. Timepoint: every 15 min in post anesthesia care unit. Method of measurement: based on modified bromage scale.	—

Measure

Time frame

Peak of sensory block. Timepoint: every 15 min until reaching equal result inthree consecutive session. Method of measurement: using Cotton alcohol method in midclavicular line from distal to proximal of body.;Needing time to reach the peak of sensory block. Timepoint: every 2 min until reaching equal result in three consecutive session. Method of measurement: using Cotton alcohol method in midclavicular line from distal to proximal of body.;Needing time to reach motor block to highest degree. Timepoint: every 15 min. Method of measurement: modified bromage scale.;Time of regression of sensory block. Timepoint: every 15 min in post anesthesia care unit. Method of measurement: time need to regression of sensory block to level of S1 using.;Time need to regression of motor block. Timepoint: every 15 min in post anesthesia care unit. Method of measurement: based on modified bromage scale.

—

Secondary

Measure	Time frame
Cardiovascular chang. Timepoint: every 10 min. Method of measurement: Using indirect blood pressure measurement via automated devise.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr.Ebrahim Ghaderi

Sanandaj Faculty of Medicine

ebrahimghaderi@muk.ac.ir+98 87 3366 6473

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026