The effect ofantenatal intramuscular adminestration of two doses of betamethasone every 12 hours on acute pulmonary complications in preterm infants born

Comparing of antenatal intramuscular adminestration of two doses of betamethasone every 12 hours with standard method every 24 hours on acute neonatal pulmonary complications in preterm infants born from women with preterm premature of membrane

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2015120415634N2

Enrollment

156

Registered

2017-09-27

Start date

2012-03-20

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Respiratory and cardiovascular disorders specific to the perinatal period. Hyaline membrane disease

Interventions

Intervention 1: Caspian tamin,Pharmaceutical Co.Rhast-IRAN,Betamethasone 4mg/ml .( In control group : Antenatal intramuscular two doses of 12 mg betamethasone every 24 hours administer to women with p

Treatment - Drugs

Caspian tamin,Pharmaceutical Co.Rhast-IRAN,Betamethasone 4mg/ml .( In control group : Antenatal intramuscular two doses of 12 mg betamethasone every 24 hours administer to women with preterm premature

Caspian tamin,Pharmaceutical Co.Rhast-IRAN,Betamethasone 4mg/ml . ( In intervention group : Antenatal intramuscular two doses of 12 mg betamethasone every 12 hours administer to women with preterm p

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Inclusion criteria: " Healthy women pregnant with singleton pregnancies and premature rupture of membranes at gestational age 26 to 34 weeks without the need for an immediate termination of pregnancy" . Exclusion criteria:" Presence of any increased blood pressure; diabetes ; chorioamnionitis ; intrauterine growth retardation; fetal anomaly; fetal distress ; steroid use by mother and any disease that corticosteroids use are contraindicated'.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Occurrence of Respiratory distress of newborn. Timepoint: First seven days of the neonatal period. Method of measurement: questionnaire.	—

Secondary

Measure	Time frame
APGAR. Timepoint: The first and fifth minutes after birth. Method of measurement: questionnaire.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactParisa Hashemi

Mahdiyeh Hospital

parisahashemi62@yahoo.com+98 21 5506 6263

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026