Skin Rejuvination. Other specified disorders of skin and subcutaneous tissue
Conditions
Interventions
Intervention 1: Topical anesthetic gel is applied to both sides of face and left for 30minutes. The patient's eyes are covered with a shield during the entire procedure. Patients are randomly assigned
which is focused to a spot size of approximately 5-10 micrometer in diameter ,the pulse duration of 0.3 -20 milliseconds and fluence from 10 to 25 J/cm2.Three treatment sessions with 1 month interval
Topical anesthetic gel is applied to both sides of face and left for 30minutes. The patient's eyes are covered with a shield during the entire procedure. Patients are randomly assigned to receive trea
Sponsors
Skin Research Center, Shahid Beheshti University of Medical Science
Eligibility
Sex/Gender
Female
Age
35 Years to 75 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria:females between 35 and 75years of age ;patients with mild to moderate facial rhytides at rest Exclusion criteria :males;females younger than 35 yerars old;pregnancy and lactatation;cosmetic procedures affecting the treatment area (e.g.,botulinum toxin,dermabrasion, chemical peeling, laser surgery, or face-lift)within the last 6months;oral isotretinoin within the last 6months; history of keloid formation,connective tissue disorders,major underlying disease,diabetes, uncontrolled hypertension, active infection in face area, personal history of skin cancer in face,unrealistic expectation,sensitivity to tetracaine or lidocaine
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Skin Elasticiy. Timepoint: before intervention,before each laser sessions,3 months after last laser. Method of measurement: resonance running time/reviscometer.;Improvement of facial rythides. Timepoint: before intervention,before each laser sessions,3 months after last laser. Method of measurement: rate of improvement measured by comparing photograph by a dermatologist.;Patient satisfaction. Timepoint: 1month after session 1&2-three month after session3. Method of measurement: questionare. | — |
Secondary
| Measure | Time frame |
|---|---|
| ?Duration of side effects. Timepoint: one week after each session. Method of measurement: number of days.;Side effects(pain-burning and stinging-erythem-edema-bulla-bleeding-crust formation-hypopigmentation-hyperpigmentation-scar-atrophy). Timepoint: one week after each session. Method of measurement: patient questionnaire,examination by a dermatologist. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSahar.dadkhahfar@gmail.com
Skin Research Center
Outcome results
None listed