The effect of labetolol on reducing bleeding during and after functional endoscopic sinus surgery(FESS)

The effect of labetolol on reducing bleeding during and after functional endoscopic sinus surgery(FESS) in patients scheduled for surgery

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT201511295225N6

Enrollment

Registered

2015-12-25

Start date

2016-01-20

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic sinusitis. Abscess empyema infection suppuration (chronic) of sinus (accessory)(nasal)

Interventions

Intervention 1: Infusion of Labetolol 1mg/h. Intervention 2: 10ml Normal Saline.

Prevention

Placebo

Infusion of Labetolol 1mg/h

10ml Normal Saline

Eligibility

Sex/Gender

All

Age

20 Years to 60 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: informed consent of patients,age between 20 and 60 years old,ASA class I & II, no contraindication for using study drugs,scheduled for functional endoscopic sinus surgery (FESS) Exclusion criteria: need for a different anesthetic regimen, any positive history for coagulation disorders, cerebral/cardiac ischemia, liver,kidney,lung,heart disease or endocrinopathies

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Bleeding. Timepoint: Amount of bleeding during surgery. Method of measurement: Checking the amount of blood in suction container at the end of surgery.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Seyed Mohammad Mireskandari

Valiasr Hospital

mireskandari@sina.tums.ac.ir+98 21 6119 2386

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026