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Comparison the effect of vaginal Misoprostol and vaginal Isoniazid for cervical ripening prior to hysteroscopy procedures

Comparison of the effect of vaginal Misoprostol and vaginal Isoniazid for cervical ripening prior to hysteroscopy procedures in postmenopausal and premenopausal women: Randomized Clinical Trial

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT2015112821506N4
Enrollment
100
Registered
2016-05-17
Start date
2015-03-21
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Abnormal uterine and vaginal bleeding, unspecified. Abnormal uterine and vaginal bleeding, unspecified

Interventions

Intervention 1: Intervention group: 12-10 hours prior to surgery, the use of vaginal misoprostol much as 400 micrograms. Intervention 2: Control group: 12-10 hours before the operation, taking 3 tabl
Diagnosis
Intervention group: 12-10 hours prior to surgery, the use of vaginal misoprostol much as 400 micrograms
Control group: 12-10 hours before the operation, taking 3 tablets of 300 mg isoniazid vaginal

Sponsors

Iran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
15 Years to 55 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: postmenopausal women and premenopausal women who have no history of vaginal delivery, not pregnant at the time of examination, no contraindication for receiving prostaglandin , no severe vaginal prolapse , no previous surgery on cervix or cervical incompetence. Exclusion criteria: history of vaginal delivery, pregnancy, severe vaginal prolapse, previous surgery on cervix, history of cervical insufficiency, simultaneous laparoscopy and cervical myoma.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Hysteroscopy entrance without cervical dilatation. Timepoint: During surgery. Method of measurement: Hagar size.

Secondary

MeasureTime frame
The number and percent of patients needs for cervical dilatation. Timepoint: During surgery. Method of measurement: Counting.;Maximum Hagar size interring without forces. Timepoint: During surgery. Method of measurement: Hagar.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactLadan Haghighi

Iran University of Medical Science

dr.ladanhaghighi@yahoo.com+98 21 6655 5447

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 18, 2026