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Effects of concurrent Omega-3 and Cranberry juice consumption on eradication of Helicobacter pylori, gastrointestinal symptoms, some serum inflammatory and oxidative stress markers in adults with Helicobacter pylori infection

Effects of concurrent Omega-3 and Cranberry juice consumption on eradication of Helicobacter pylori, gastrointestinal symptoms, some serum inflammatory and oxidative stress markers in adults with Helicobacter pylori infection

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20151128025274N3
Enrollment
92
Registered
2018-01-28
Start date
2018-01-29
Completion date
Unknown
Last updated
2020-05-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Helicobacter pylori. Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters

Interventions

Intervention 1: Intervention group: Two weeks of helicobacter pylori triple therapy, including daily intake of pantoprazole 80 mg , amoxicillin 2 g, bismuth 8 mg and clarithromycin 1 g + cranberry jui

Sponsors

Ahvaz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Age 18 to 65 years old Helicobacter pylori infection Gastrointestinal complaints Body mass index 18.5 to 35 kg / m2

Exclusion criteria

Exclusion criteria: Having a history of drug therapy to eradicate Helicobacter pylori infection Stomach surgery History of peptic ulcer and gastrointestinal malignancies Having any disease that causes inflammation and increased levels of inflammatory markers, such as diabetes, cardiovascular disease, respiratory infections such as asthma and ... Getting immunodeficiency diseases Developing chronic diseases requiring drug treatment Taking medications other than prescription drugs Receiving antibiotics or proton pump inhibitors or H2 blockers over the past 2 months Taking omega supplementation At least 3 months before the start of the study Use of any diet supplements During the study 3 months before the start of the study Changes in the diet during the study period Consumption of less than 80% of the supplements delivered to the patient during the study period.

Design outcomes

Primary

MeasureTime frame
Negative cases of Helicobacter pylori infection. Timepoint: Three weeks after the end of treatment. Method of measurement: Checking of H.Pylori stool antigen.;Scale of gastrointestinal complaints questionnaire from Helicobacter pylori infection. Timepoint: Before and at the end of the study. Method of measurement: Questionnaire.;Serum levels of Il-17, TGFß1 and INF-?. Timepoint: Before and at the end of the study. Method of measurement: ELISA method.;Serum levels of TAC and MDA. Timepoint: Before and after study. Method of measurement: ELISA method.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactLeila Maghsoumi-Nourozabad

Ahvaz University of Medical Sciences

l.maghsumi55@gmail.com+98 61 3373 8330

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 25, 2026