Evaluation of IV Ketorolac with Fentanyl Transdermal Patch effectiveness in relieving pain in biliary colic attacks

Compare the efficacy of intravenous ketorolac and fentanyl transdermal patch for pain relief in patients with inflammation of the gallbladder colic attacks

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT2015112725261N1

Enrollment

260

Registered

2016-02-28

Start date

2016-02-20

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

biliary colic. Calculus of bile duct without cholangitis or cholecystitis

Interventions

Intervention 1: Ketorolac IV 30 mg and Transdermal pach with out drugs (Placebo) to a group of patients given only once . Intervention 2: Transdermal Fentanyl 75 mic/gr and plaebo ampuls for the secon

Treatment - Drugs

Ketorolac IV 30 mg and Transdermal pach with out drugs (Placebo) to a group of patients given only once .

Transdermal Fentanyl 75 mic/gr and plaebo ampuls for the second group of patients who are prescribed only once

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: 1 - MINIMUM AGE 18 and maximum65 years; 2 -Having pain paunch of evaluation by the physician or assistant emergency medicine as biliary colic diagnose; 3 - Unprecedented of stone of the bladder by National rivalries diagnose; exclusion criteria: 1 - Aged under 18 and Bali 65 years; 2 - The temperature above 38 ºc; 3 - Allergic to ketorolac and other nsaid; 4 - Sensitivity to transdermal fentanyl gasteroentrology; 5 - Patients that tired King outside; 6 - Treatment of anti-making blood in 4 recent weeks; 7 - History ulcers active during 6 recent months; 8 - The history of the disease of blood planning provider; 9 - Patients with safety system, disease of the hepatitis; 10 - Disease of the renal arteries; 11 - Medical problem, acute heart patients; 12 - Ppregnant women; 13 - A history of peptic ulcer and pancratit; 14 - Addicts to drugs, mopper foods or any inhalants something; 15 - failure to confirm biliary colic diagnosed with sonography; 16 -Any problems normal or abnormal in your skin that may attract medicine the skin affected the "having a lot of hair or skin disease; 17 -Receive any kind of pain medication or mopper foods in 8 hours before entering the emergency room

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Pain. Timepoint: 0 and 30 and 60 min and 3-4 h after intervetion. Method of measurement: Numeric Rating Scale metod.	—

Secondary

Measure	Time frame
Side effects of Ketorolac and Fentanyl. Timepoint: 0 and 30 and 60 min and 3-4 h after intervetion. Method of measurement: Vital sign,s.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFarhad Zarei Ghanavati

Ahvaz Jundishapur University of Medical Sciences

zarei.f@ajums.ac.ir+98 61 3161

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026