Efficacy of vitamin C in prevention of mucositis

Efficacy of vitamin C in prevention of chemoradiation-induced mucositis in the patients with head and neck cancer

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2015112525239N1

Enrollment

Registered

2015-12-23

Start date

2015-12-22

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Head and neck cancer. Neoplasm of uncertain or unknown behaviour of other and unspecified sites

Interventions

Intervention 1: In Intervention Group: we will give each day a vitamin C tablet 250mg production of Osvah Pharmaceutical Company for a month. Intervention 2: In Control Group: we will give a placebo o

Prevention

Placebo

In Intervention Group: we will give each day a vitamin C tablet 250mg production of Osvah Pharmaceutical Company for a month.

In Control Group: we will give a placebo of Vitamin C tablet 250 mg production of Osvah Pharmaceutical Company each day for a month.

Eligibility

Sex/Gender

All

Age

15 Years to 70 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: age between 15 to 70 years; Cisplatin regimen with 45-60 Gy radiation. Exclusion criteria: any oral disease like oral active infections; candidiasis; artificial teeh; using tobacco; smoking; alcohol use; using opioids; and fever more than 38.5 ° C.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Severity of mucositis. Timepoint: weekly for 4 weeks. Method of measurement: WHO Toxicity Criteria.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Solmaz Sadeghi

Tabriz University Of Medical Sciences

afsaneh7927sgh@gmail.com+98 41 3335 5921

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026