Chronic sinusitis. J32Chronic sinusitis Incl.: abscess, empyema, infection, suppuration (chronic) of sinus (accessory)(nasal
Conditions
Interventions
Intervention 1: Intervention group: Oral drug: Marjoram and licorice herbal tea, dose: 5 grams of pack contains 3 grams of leaves of marjoram and 2 grams of licorice root, every 8 hours, the duration
If there is no improvement in symptoms for up to 12 weeks will continue. How to use: patient should be infuse the contents of each packet with 200 ml of boiling water in the pot for 20 minutes and aft
if there is no improvement in symptoms for up to 12 weeks will continue. Education: patients of this group on the basis of written instructions that will be placed at their disposal, will be avoided f
along with daily nose irrigation with normal saline in the morning and evening. If there is no improvement, a systemic steroids will be administrated (prednisone tablets 1 mg / kg
that will be tapered within a short time). If there is evidence of purulent sinusitis, antibiotic treatment with azithromycin capsules of 250 mg daily for 4 weeks will be added to the treatment protoc
Treatment - Drugs
Intervention group: Oral drug: Marjoram and licorice herbal tea, dose: 5 grams of pack contains 3 grams of leaves of marjoram and 2 grams of licorice root, every 8 hours, the duration of treatment (c
Control group: Prescription drugs include: Inhaled corticosteroid (Fluxinase), at a rate of 2 inhalations per day
Sponsors
Vice Chancellery for Research of Mashhad University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 49 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Two criteria of the main criteria (including: nasal obstruction or congestion; anterior or posterior nasal secretion; facial pain or pressure; and reduction or loss of smell) or one major criterion and two minor criteria (including dental pain; cough; pain; pressure or fullness feel in ears; fatigue; headache or halitosis) for more than 12 weeks during the past 12 months. Exclusion criteria: Chronic sinusitis along with acute bacterial infections of the respiratory tract; Chronic sinusitis along with anatomical obstructions requiring surgery; Sensitivity or contraindication to the drug components; Pregnancy; Immunodeficiency; The presence of high blood pressure (hypertension history or blood pressure on admission greater than 140/90 mm Hg)
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Symptoms of chronic sinusitis. Timepoint: Baseline and sixth, eighth and twelfth week after intervention. Method of measurement: SNOT22 Questionnaire. | — |
Secondary
| Measure | Time frame |
|---|---|
| Paranasal sinuses status. Timepoint: Before the intervention and twelve weeks after beginning intervention. Method of measurement: Lund-Mackey Score.;Symptoms of cold Coryza (Zokam) and Catarrh (Nazlah). Timepoint: Before the intervention and twelve weeks after intervention beginning. Method of measurement: cold Coryza (Zokam) and Catarrh (Nazlah) questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Mohammad Reza Mehri
Mashhad University of Medical Sciences, Faculty of Traditional and Complementary Medicine
Outcome results
None listed