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INH plus misoprostol vs. misoprostol alone for early medical abortion

INH plus misoprostol vs. misoprostol alone for early medical abortion: clinical trial

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT2015112421506N3
Enrollment
100
Registered
2016-02-01
Start date
2015-09-01
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Abortion. Miscarriage

Interventions

Intervention 1: In case group vaginal administration of isonicotinic acid hydrazide (INH) (1800mg) + misoprostol (800 mg sublingual 8hrs later) which will be repeated every 3hrs upto 3times in 12hours
Treatment - Drugs
In control group 800 mcg sublingual misoprostol given that in the absence of pain and vaginal bleeding occurs every three hours. (Maximum of three doses in 12 hours)
In case group vaginal administration of isonicotinic acid hydrazide (INH) (1800mg) + misoprostol (800 mg sublingual 8hrs later) which will be repeated every 3hrs upto 3times in 12hours in as needed.

Sponsors

Iran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: All pregnant women with gestational age less than or equal to 91 days based on sonography and lmp that refereed to Akbar Abadi hospital and were candidates for the termination of pregnancies (blighted ovum, missed abortion) or medical abortion license included this study.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Abortion time. Timepoint: During the intervention. Method of measurement: Hour.

Secondary

MeasureTime frame
Vomiting. Timepoint: During the intervention. Method of measurement: Visual Analogue Scale.;Diarrhea. Timepoint: During the intervention. Method of measurement: Visual Analogue Scale.;Fever. Timepoint: During the intervention. Method of measurement: Celsius degrees.;Nausea. Timepoint: During the intervention. Method of measurement: Visual Analogue Scale.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Ladan Haghighi

Iran University of Medical Science

dr.ladanhaghighi@yahoo.com+98 21 6650 9283

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026