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Comparison of the three types of drugs to reduce propofol pain

Comparisson effect of pretreatment with ondansetron, lidocaine and paracetamol drugs on pain reduction due to interavenous injectionof Propofol

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2015112325202N1
Enrollment
164
Registered
2016-01-31
Start date
2015-07-23
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acut pain after propofol injection. pain, Vomiting, nausia

Interventions

Intervention 1: Intervention 1: Paracetamol: Closing pressure cuff on the arm on the same side and blowing tourniquet pressure to 70 mm Hg, partial occlusion of the venous system has been established
Treatment - Drugs
Placebo
Control group: distilled water all steps will be similar to the intervention group
Intervention 1: Paracetamol: Closing pressure cuff on the arm on the same side and blowing tourniquet pressure to 70 mm Hg, partial occlusion of the venous system has been established and this drug wi
Intervention 2:ondancetronl: Closing pressure cuff on the arm on the same side and blowing tourniquet pressure to 70 mm Hg, partial occlusion of the venous system has been established and this drug wi
Intervention 3: lidocain: Closing pressure cuff on the arm on the same side and blowing tourniquet pressure to 70 mm Hg, partial occlusion of the venous system has been established and this drug will

Sponsors

parisa shirzad
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: " age 18 to 65 years" "patients with ASA class 1 and 2" " patients undergoing elective surgery" Exclusion criteria:" (1) patients with ASA class of 3 or higher 2. Patients with a history of HTN and DM 3. Patients with a history of narcotic or psychotropic abuse or NSAID 4. The patient who are contraindicate for propofol, ondansetron, paracetamol and lidocaine drugs

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Reduce the pain of Propofol injection. Timepoint: Along with propofol infusion in 20 seconds. Method of measurement: four-point verbal rating scale = VRS) which contains no pain = 0 , mild= 1 , moderate= 2 and severe =score 3 (by tearing or rejection injected organs or patient complain of pain or frown).

Secondary

MeasureTime frame
Check of pain and swelling and allergic reactions of drugs within 2 hours after injection were recorded in questionnair. Timepoint: within 2 hours after injection of drugs. Method of measurement: Observation and question.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactParisa Shirzad

Hamadan University Of Medical Science

Fairyborn7@yahoo.com+98 818138378247

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026