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Effectiveness of microneedling in treatment of striae

Is Microneedling alone or with topical tretinoin or PRP effective in striae distensae treatment?A Randomized clinical trial

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT2015112322468N2
Enrollment
99
Registered
2016-02-03
Start date
2016-02-20
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

striae distensae. Striae Atrophicae

Interventions

Intervention 1: Group1:Microneedling-monthly for 4 months. Intervention 2: Group2: Combination of microneedling and topical PRP_ monthly for 4 months. Intervention 3: Group3: Microneedling monthly for
Group1:Microneedling-monthly for 4 months
Group2: Combination of microneedling and topical PRP_ monthly for 4 months
Group3: Microneedling monthly for 4 months with daily use of tretinoin 0.05 cream

Sponsors

Iran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 50 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: non-pregnant,20-50 year old women with striae distensae due to previous pregnancies that refer to the dermatologic clinic of rasoul akram hospital. Exclusion criteria:pregnancy; platelet dysfunction; severe thrombocytopenia( less than 50000); local inflamatory skin disorders or active herpatic infection in procedure site.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Size and depth of striae. Timepoint: Monthly for 4 months and then 3 months later. Method of measurement: Davey method and asking from patient.

Secondary

MeasureTime frame
Local side effects. Timepoint: Monthly for 4 months and then 3 months later. Method of measurement: Clinical examination.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammadreza Ghassemi

Hazrat Rasoul Akram Hospital

ghassemi.mr@iums.ac.ir+98 21 6435 2528

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026