The effect of estradiol treatment duration on pregnancy outcome

Comparison of the duration of treatment with estradiol in the endometrial preparation in the freezing embryo transfer cycle and its effect on pregnancy outcome

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20151123025202N8

Enrollment

140

Registered

2020-06-19

Start date

2020-07-22

Completion date

Unknown

Last updated

2020-07-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Women infertility]. Female infertility of uterine origin

Interventions

Intervention 1: Intervention group:After measuring estrogen and progesterone levels, from the second or third day of the menstrual cycle, estradiol will be given orally at a dose of 4-6 mg. After a we

Eligibility

Sex/Gender

Female

Age

No minimum to 40 Years

Inclusion criteria

Inclusion criteria: Patients candidate for embryo transfer Have at least two well quality embryos for transfer Having normal pelvic cavity

Exclusion criteria

Exclusion criteria: Uncontrolled chronic disease Patients with donated ovum or embryos poor ovarian response Have a history of more than two failed transfers

Design outcomes

Primary

Measure	Time frame
Chemical Pregnancy. Timepoint: Two weeks after embryo transfer. Method of measurement: B-HCG Test.;Clinical Pregnancy. Timepoint: 10 weeks after chemical pregnancy. Method of measurement: Sonography.	—

Secondary

Measure	Time frame
Abortion. Timepoint: first trimester of pregnancy. Method of measurement: Sonography.;Drug side effects. Timepoint: during treatment period. Method of measurement: Clinical examination and interview.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAbbas Moradi

Hamedan University of Medical Sciences

a.moradi@umsha.ac.ir+98 81 3838 0097

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026