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The effect of hormone therapy on tinnitus in menopausal women

Evaluation of the effect of hormone replacement therapy on tinnitus in menopausal women.

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20151123025202N46
Enrollment
40
Registered
2025-07-29
Start date
2025-08-23
Completion date
Unknown
Last updated
2025-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Tinnitus. Tinnitus

Interventions

Intervention 1: Intervention group: They will receive 0.625 mg of conjugated estrogens and 2.5 mg of medroxyprogesterone daily for three months. Intervention 2: Control group: They will receive one pl

Sponsors

Hamedan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
50 Years to No maximum

Inclusion criteria

Inclusion criteria: Female gender Menopause within the last 10 years Having the patient's consent to participate in the study

Exclusion criteria

Exclusion criteria: Having depression History of calcium, vitamin, and magnesium intake two months before intervention Tinnitus caused by medication side effects Suspicion and diagnosis of tumoral lesions Patients with conductive or mixed hearing loss

Design outcomes

Primary

MeasureTime frame
Change in the intensity of tinnitus. Timepoint: Before treatment and at the end of the third month of treatment. Method of measurement: With visual analog scale.;Changes in disability scores due to tinnitus. Timepoint: Before treatment and at the end of the third month of treatment. Method of measurement: With the Tinnitus Tinnitus Handicap Inventory (THI).;Loudness and frequency of tinnitus. Timepoint: Before treatment and at the end of the third month of treatment. Method of measurement: Audiometric test.

Secondary

MeasureTime frame
Occurrence of drug side effects. Timepoint: During treatment. Method of measurement: Questioning the patient.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAbbas Moradi

Hamedan University of Medical Sciences

a.moradi@umsha.ac.ir+98 81 3838 0097

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026