Acne vulgaris. Acne vulgaris
Conditions
Interventions
Intervention 1: Intervention group: Tacrolimus ointment 0.1% will be used topically once a night for 8 weeks. Intervention 2: Intervention group: 0.5% timolol maleate solution will be used topically o
Sponsors
Hamedan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Age above 18 years Consent to participate in the study
Exclusion criteria
Exclusion criteria: History of allergy to tacrolimus and timolol History of using anti-acne drugs within 3 months before the treatment process Pregnant and lactating mothers bronchial asthma, severe COPD, sinus bradycardia, 2nd and 3rd degree heart block and heart failure
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Erythema. Timepoint: Before treatment, at the end of week 4 and at the end of week 8 of treatment. Method of measurement: Take a picture of lesions and and compare based on Clinical Erythema Assessment scale by dermatologist. | — |
Secondary
| Measure | Time frame |
|---|---|
| Side effects of itching, burning, scaling and redness. Timepoint: 4th and 8th week of treatment. Method of measurement: Clinical examination and asking the patient about complications. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAbbas Moradi
Hamedan University of Medical Sciences
Outcome results
None listed