Prevention of hematoma, swelling and pain after carpal tunnel syndrome surgery with tranexamic acid

Evaluation of the effect of topical tranexamic acid administration in preventing hematoma, swelling and pain after carpal tunnel syndrome surgery

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20151123025202N32

Enrollment

Registered

2023-10-24

Start date

2023-12-22

Completion date

Unknown

Last updated

2023-11-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Carpal tunnel syndrome. Carpal tunnel syndrome

Interventions

Intervention 1: Intervention group: After the completion of carpal tunnel syndrome surgery, two ampoules of tranexamic acid (2 grams) will be injected into the flexor sheet. Intervention 2: Control gr

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Diagnosis of bilateral carpal tunnel syndrome that requires surgery Not using anti-anxiety, hypnotic and sedative drugs Hemoglobin >10

Exclusion criteria

Exclusion criteria: History of coagulopathy Allergy to tranexamic acid Contraindication for spinal anesthesia and allergy to anesthetics and other drugs.

Design outcomes

Primary

Measure	Time frame
Hematoma. Timepoint: 24 hours, 2 weeks, 1 month and 3 months post operation. Method of measurement: Clinical Examination.;Swelling. Timepoint: 24 hours, 2 weeks, 1 month and 3 months post operation. Method of measurement: Clinical Examination.;Pain. Timepoint: 24 hours, 2 weeks, 1 month and 3 months post operation. Method of measurement: Visual Analogue Scale.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAbbas Moradi

Hamedan University of Medical Sciences

a.moradi@umsha.ac.ir+98 81 3838 0097

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026