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Effectivness of Topical Furesemaide chronic on rhinosinusitis surgery

Study on Effectivness of Topical Furesemaide administration on intraoperative blood loss and quality of the surgical field during functional endoscopic sinus surgery in patients with chronic rhinosinusitis

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20151123025202N3
Enrollment
72
Registered
2019-11-23
Start date
2019-11-22
Completion date
Unknown
Last updated
2019-12-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chronic rhino sinusitis. js32.9

Interventions

Intervention 1: Intervention group: receive one Puff of Furzemide spray (20 micrograms per puff equivalent to 40 micrograms) in each nasal side daily from one week before surgery. Intervention 2: Cont

Sponsors

Hamedan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Patients with chronic rhinosinusitis with or without polyposis (primary or recurrent) Ages between 18 and 60 years Normalization of PT, PTT, INR, BT, CT and platelet count

Exclusion criteria

Exclusion criteria: have Bleeding disorders such as uncontrolled hemophilia Uncontrolled history of thromboembolic events Uncontrolled Receive heparin at 48 hours before surgery ake aspirin within 3 days before surgery Allergies to Furesemaide Liver Cirrhosis Systemic diseases such as hypertension, diabetes, heart failure Patients with sinonasal tumor side effects of Furesemaide acute or chronic renal failure Cardiac stent

Design outcomes

Primary

MeasureTime frame
Reduce bleeding in surgery site. Timepoint: end of surgery time. Method of measurement: The amount of blood collected in the suction bottle (after deduction of normal saline volume) and the weight of blood-stained packs.

Secondary

MeasureTime frame
Quality of vision of the surgical field. Timepoint: during the surgery. Method of measurement: with Boezaart Grading questionair.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAbbass Moradi

Hamedan University of Medical Sciences

a.moradi@umsha.ac.ir+98 81 3823 5480

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026