anesthetics effect of mouth wash Amitriptyline

Evaluation of the effect of niosomal mouth wash Amitriptyline as local anesthetics in patients with oral mucositis due to radio therapy or chemo therapy and comparison with mouth wash Benzydamine HCl

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2015112123529N1

Enrollment

Registered

2015-11-21

Start date

2014-03-20

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anaesthesia. Dissociative anaesthesia and sensory loss

Interventions

Intervention 1: intervention group1: niosomal mouth wash Amitriptyline(Manufacturer: Darou Pakhsh Pharmaceutical Mfg Co.) ,15 cc for 30 seconds qd. Intervention 2: intervention group2: mouth wash Amit

Treatment - Drugs

intervention group1: niosomal mouth wash Amitriptyline(Manufacturer: Darou Pakhsh Pharmaceutical Mfg Co.) ,15 cc for 30 seconds qd

intervention group2: mouth wash Amitriptyline(Manufacturer: Darou Pakhsh Pharmaceutical Mfg Co.),15 cc for 30 seconds qd

control group: mouth wash Benzydamine HCl(Manufacturer: Darou Pakhsh Pharmaceutical Mfg Co.),15 cc for 30 seconds qd

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: inclusion criteria: patients with oral mucositis due to radiotherapy or chemotherapy; having pain or burning mouth while study. exclusion criteria: allergic to three-cyclic antidepressants.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Severity. Timepoint: befor intervention and in 1, 5, 10, 30 and 60 minutes after intervention. Method of measurement: VAS form.	—

Secondary

Measure	Time frame
-. Timepoint: -. Method of measurement: -.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Elahe Tahmasebi

Kerman University of Medical Sciences

e_tahmasbi@collegian.kmu.ac.iR; elahe.tahmasebi.delfan@gmail.com+98 34 3213 3454

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026