Serum interleukin changes in gastric bypass surgery, before and after general anesthesia with isoflurane and propofol .

Comparison of changes in serum interleukin, in patients with morbid obesity under laparoscopic gastric bypass surgery, before and after general anesthesia with isoflurane and propofol.

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT2015111812642N22

Enrollment

Registered

2015-12-03

Start date

2015-03-21

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Laparoscopic Gastric Bypass. Morbid obesity

Interventions

Intervention 1: In the first group, 1.2% isoflurane is used as a maintenance of anesthesia during surgery. Intervention 2: In the second group, intravenous propofol is used as a maintenance of anest

Prevention

In the first group, 1.2% isoflurane is used as a maintenance of anesthesia during surgery.

In the second group, intravenous propofol is used as a maintenance of anesthesia during surgery.

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Patients undergoing laparoscopic gastric bypass; ASA Class II -III; morbid obesity (BMI> = 35 kg / m2); Exclusion criteria: With cardiovascular and respiratory diseases, drug and alcohol abuse, renal failure, liver dysfunction and autoimmune disease, diabetes or asthma disease, regular use of steroids and NSAID; core temperature greater than 37 ° C, the number of cells white More than 10 thousand

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Interleukin 10. Timepoint: Before the induction of anesthesia and end of anesthesia. Method of measurement: In blood plasma sample, by ELISA, according picogeram per mililiter.;TNF Alfa. Timepoint: Before the induction of anesthesia and end of anesthesia. Method of measurement: In blood plasma sample, by ELISA, according picogeram per mililiter.	—

Secondary

Measure	Time frame
Age. Timepoint: Before entering the study. Method of measurement: Based on the number of years of life on the basis of year.;Height. Timepoint: Before enteiring to study. Method of measurement: Based on the information in the file and on the basis of centimeter.;Wieght. Timepoint: Before entering to study. Method of measurement: Based on the information in the file and on the basis of kilogeram.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSeyed Reza Bani Hashemi

Razi Vaccine and Serum Research Institute

R.banihashemi@rvsri.ac.ir00982634570038

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026