Fatigue. Malaise and fatigue
Conditions
Interventions
Intervention 1: Amantadine given to the active drug group
100 mg Capsule
one capsule per day for 1 month. Intervention 2: palacebo given to placebo group
placebo capsule, one per day for
Treatment - Drugs
Placebo
Amantadine given to the active drug group
100 mg Capsule
one capsule per day for 1 month
palacebo given to placebo group
placebo capsule, one per day for 1 month
Sponsors
Deputy of research and technology developement, Ahvaz Jundishapur University of Medical Sciences
Eligibility
Sex/Gender
Male
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: subjects who experience fatigue post methamphetamine cessation (diagnosis made by DSMIV-TR criteria); no other disorders like diabetes, hypertention and hyper or hypo thyroidism; no use of alcohol or drugs; taking another drug that has interaction with amantadine ;age between 18 and 40. exclusion criteria: patients who don't sign the consent form; patients that don't have a good drug compliance in the process of the trial; developement of any side effect or condition that needs discontinuation of amantadine
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fatigue. Timepoint: prior to intervention and 1 month after intervention. Method of measurement: FSS score from the test. | — |
Secondary
| Measure | Time frame |
|---|---|
| Adveres drug reaction. Timepoint: 1 month. Method of measurement: patient report. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactReza Hassanvand
Pharmacy school
Outcome results
None listed