Comparison the effect of inhalation and intravenous fentanyl on pain severity of patients with upper or lower limbs fracture

The effect of inhalation and intravenous fentanyl on pain severity of patients with limb fracture

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2015111425027N1

Enrollment

212

Registered

2016-05-11

Start date

2015-08-23

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pain. Pain in limb

Interventions

Intervention 1: Patients in intervention group will receive 1 µgr/kg intravenous fentanyl of 50 µgr/ml solution and 5 ml normal saline via inhalation. Intervention 2: Patients in control group will re

Treatment - Drugs

Patients in intervention group will receive 1 µgr/kg intravenous fentanyl of 50 µgr/ml solution and 5 ml normal saline via inhalation.

Patients in control group will receive 5 ml intravenous normal saline and 4 µgr/kg fentanyl of 50 µgr/ml solution in combination with 5 ml normal saline via inhalation.

Eligibility

Sex/Gender

All

Age

15 Years to 55 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: age range of 15 to 55 years; having upper and lower limbs fracture. Exclusion criteria: using of antisycotic, sedative, tricyclic antidepressant, selective serotonin reuptake inhibitor, monoamine oxidase inhibitor drugs; having addiction to drugs or opioids; having acute and chronic renal diseases, liver and heart diseases, respiratory diseases (upper and lower respiratory system infection, asthma, chronic obstructive pulmonary diseases); having allergy; being pregnant; fentanyl contraindication.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Pain severity. Timepoint: 5, 10, 15, 30 and 60 minutes. Method of measurement: Visual analogue scale.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammadreza Malaki Varaki

Ahwaz Judishapur University of Medical Sciences

Drmalaki676@yahoo.com+98 912 278 2787

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026