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Evaluation of The Iron Effect on Thyroid Function in Women

Evaluation of The Iron Effect on Thyroid Function in Women with Hypothyroidism

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20151114025031N7
Enrollment
94
Registered
2018-02-24
Start date
2017-10-29
Completion date
Unknown
Last updated
2018-03-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Other hypothyroidism. Other hypothyroidism

Interventions

Intervention 1: Intervention group: Levothyroxine with 100 mg iron per day for 2 months. Intervention 2: Control group: Levothyroxine with 100 mg placebo per day for 2 months.

Sponsors

Arak University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 70 Years

Inclusion criteria

Inclusion criteria: Hypothyroidism with TSH in the range of 0.05 to 5 mu/l, which with the use of levothyroxine for at least 6 months or more remains in this range. Female Between 20 to 70 years old

Exclusion criteria

Exclusion criteria: Pregnancy that occurs during the study Breastfeeding that occurs during the study Chronic diseases, such as liver and kidney disease, that occurs during the study Gi intolerance to iron tablets Patients with thyroid cancer

Design outcomes

Primary

MeasureTime frame
T3 Level. Timepoint: Before and two months after intervention. Method of measurement: enzyme-linked fluorescence assay (ELFA).;T4 Level. Timepoint: Before and two months after intervention. Method of measurement: enzyme-linked fluorescence assay (ELFA).;TSH Level. Timepoint: Before and two months after intervention. Method of measurement: enzyme-linked fluorescence assay (ELFA).;Ferritin Level. Timepoint: Before and two months after intervention. Method of measurement: enzyme-linked fluorescence assay (ELFA).;Hemoglobin Level. Timepoint: Before and two months after intervention. Method of measurement: enzyme-linked fluorescence assay (ELFA).;Serum Iron Level. Timepoint: Before and two months after intervention. Method of measurement: enzyme-linked fluorescence assay (ELFA).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Zahra Shiravand

Arak University of Medical Sciences

z.shiravand1989@yahoo.com+98 86 3417 3601

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026