The Comparison between Propofol-Ketamine with Sodium Thiopental-Fentanyl effectiveness in Adult Procedural Sedation and Analgesia in Shariati, Sina and Imam-Khomeini Emergency Departments

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT2015111325025N1

Enrollment

Registered

2016-01-03

Start date

2016-01-05

Completion date

Unknown

Last updated

2020-07-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Procedural sedation and analgesia.

Interventions

Intervention 1: group A: Propofol-Ketamine administration Ketamine Hydrochloride (Rotexmedia Trittau-Germany) 0.5 mg/kg Propofol Lipuro 1% (B. Braun Melsungen AG) 0.5 mg/kg Repeated half doses every 5

Eligibility

Sex/Gender

All

Age

18 Years to 100 Years

Inclusion criteria

Inclusion criteria: All adults of American Society of Anesthesiologist Class (ASA) class I-II of Procedural Sedation and Analgesia

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Comparison between 2 sedative regimen efficacy. Timepoint: During sedation for a painful procedure. Method of measurement: Ramsay Sedation Scores are documented in the questionnaire.	—

Secondary

Measure	Time frame
Cardiovascular/respiratory adverse events. Timepoint: During and after sedation (every 5 minutes) up to achievement of baseline Ramsay score. Method of measurement: Cardiac monitoring and pulse oximetry.;Patient and provider satisfaction. Timepoint: After the end of sedation. Method of measurement: Visual Analog Scale.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Maryam Bahreini

Tehran University of Medical Sciences

bahreinimaryam@gmail.com+98 216312413

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026