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Comparing the healing effect of dried and acellular human amniotic membrane with Mepitel as coverage of skin graft donor areas

Comparing the healing effect of dried and acellular human amniotic membrane with Mepitel as coverage of skin graft donor areas

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT201511118177N12
Enrollment
30
Registered
2016-01-29
Start date
2013-10-08
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Skin wound. Open wound of unspecified body region

Interventions

Intervention 1: Intervention 1: wound covering of donor site with dry amnion, 4 days after surgery dressing will be changed every 4 days up to 12 days. Intervention 2: Intervention 2: wound covering o
Treatment - Other
Intervention 1: wound covering of donor site with dry amnion, 4 days after surgery dressing will be changed every 4 days up to 12 days
Intervention 2: wound covering of donor site with acellular amniotic membrane, 4 days after surgery dressing will be changed every 4 days up to 12 days
Control group: wound covering of donor site with mepitel, dressing will be changed after 8 and 12 days after surgery

Sponsors

Royan Institute for Stem Cell Biology and Technology (RI-SCBT)
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: age 16-60 years, requiring skin grafting, informed consent form completion Exclusion criteria: having underlying disease

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Wound healing. Timepoint: observation, examination and photography on days 4, 8 and 12 after surgery. Method of measurement: observation, examination and photography.

Secondary

MeasureTime frame
Pain. Timepoint: Days four, eight and twelve after surgery. Method of measurement: Visual analog scale.;Infection. Timepoint: Days four, eight and twelve after surgery. Method of measurement: Observation and examination.;Scar. Timepoint: Three and six months after surgery. Method of measurement: Vancouver scale.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammad Javad Fatemi

Hazrat Fatima Hospital

mj-fatemi@sins.tums.ac.ir+98 21 8871 7272

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 24, 2026