Comparison of clinical and Spirometric response between nebulized salbutamol _ magnesium sulfate and nebulized salbutamol alone in acute asthma attack

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT2015111015446N8

Enrollment

146

Registered

2015-11-27

Start date

2014-03-22

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute attack asthma. Asthma

Interventions

Intervention 1: The intervention group were recorded at 0, 20, 40, 60 spirometric values of FEV1 and PEFR were measured and recorded. For each patient to record the values of FEV1 and PEFR, 3 times a

Treatment - Drugs

The intervention group were recorded at 0, 20, 40, 60 spirometric values of FEV1 and PEFR were measured and recorded. For each patient to record the values of FEV1 and PEFR, 3 times a spirometry perfo

The control group were recorded at 0, 20, 40, 60 spirometric values of FEV1 and PEFR were measured and recorded. For each patient to record the values of FEV1 and PEFR, 3 times a spirometry performed

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: patients with clinical and para-clinical asthma has been confirmed; age 18 years and maximum 65 years. Exclusion criteria: COPD; CHF; pneumonitis, pulmonary disease lightweight, pregnancy, lactation, is febrile, receiving salbutamol 6 hours before the visit.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Clinical state. Timepoint: Before intervention,20,40,60,minutes after intervention. Method of measurement: Base on alert status,talking,wizing,use of respiratory mu.;Forced Expiratory Volum in First Secend (FEV1). Timepoint: Before intervention,20,40,60,minutes after intervention. Method of measurement: Mililiter with use of Peak Flow Meter.;Peak Expiratory Flow Rate(PEFR). Timepoint: Before intervention,20,40,60 minutes after intervention. Method of measurement: Mililiter with use of Peak Flow Meter.	—

Measure

Time frame

Clinical state. Timepoint: Before intervention,20,40,60,minutes after intervention. Method of measurement: Base on alert status,talking,wizing,use of respiratory mu.;Forced Expiratory Volum in First Secend (FEV1). Timepoint: Before intervention,20,40,60,minutes after intervention. Method of measurement: Mililiter with use of Peak Flow Meter.;Peak Expiratory Flow Rate(PEFR). Timepoint: Before intervention,20,40,60 minutes after intervention. Method of measurement: Mililiter with use of Peak Flow Meter.

—

Secondary

Measure	Time frame
Blood pressure. Timepoint: Before intervention,20,40,60 minutes after intervention. Method of measurement: mm Hg.;Pulse Rate. Timepoint: Before intervention,20,40,60 minutes after intervention. Method of measurement: Rate/Minutes.;Respiratory Rate. Timepoint: Before intervention,20,40,60 minutes after intervention. Method of measurement: Rate/Minutes.;Saturation of arterial blood oxygen (SO2 %). Timepoint: Before intervention,20,40,60 minutes after intervention. Method of measurement: with Pulse Oximetry.	—

Measure

Time frame

Blood pressure. Timepoint: Before intervention,20,40,60 minutes after intervention. Method of measurement: mm Hg.;Pulse Rate. Timepoint: Before intervention,20,40,60 minutes after intervention. Method of measurement: Rate/Minutes.;Respiratory Rate. Timepoint: Before intervention,20,40,60 minutes after intervention. Method of measurement: Rate/Minutes.;Saturation of arterial blood oxygen (SO2 %). Timepoint: Before intervention,20,40,60 minutes after intervention. Method of measurement: with Pulse Oximetry.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactDR.Hasan Motamed

Emergency Medicine Assistant Professor

Hasan_motamed@yahoo.com+98 61 3374 3079

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026