Effects of pre-bronchoscopy administration of intravenous hydrocortisone in patients with chronic obstructive pulmonary disease

Effects of pre-bronchoscopy administration of intravenous hydrocortisone in patients with chronic obstructive pulmonary disease: A randomized, double blind, placebo controlled trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2015110922566N1

Enrollment

Registered

2015-12-30

Start date

2015-10-23

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chronic obstructive pulmonary disease. chronic lower respiratory diseases

Interventions

Intervention 1: 200 mg hydrocortisone diluted in 10 cc iv 2 hour before bronchoscopy. Intervention 2: 10 cc normal salin iv 2 hour before bronchoscopy.

Treatment - Drugs

200 mg hydrocortisone diluted in 10 cc iv 2 hour before bronchoscopy

10 cc normal salin iv 2 hour before bronchoscopy

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: inclusion criteria; " diagnosed with chronic obstructive pulmonary disease and FEV1/FVC ratio less than 70%" " history of smoking" "the need of bronchoscopy for the diagnostic studies like hemoptysis, tuberculosis or lung mass". exclusion criteria; "diagnosis of asthma,cystic fibrosis" " oral or intravenous corticosteroid therapy or inhaled corticosteroid dose of 600 micrograms or more per day" " therapeutic bronchoscopy" " intubation".

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Vital sign. Timepoint: pre-bronchoscopy and 1 hour after bronchoscopy. Method of measurement: termometer,choronometer,sphygmanometer.;Cough. Timepoint: pre-bronchoscopy and 1 hour after bronchoscopy. Method of measurement: numboring score from 1 to 10.;Spirometery. Timepoint: pre-bronchoscopy and 1 hour after bronchoscopy. Method of measurement: spirometer.;Saturaton of blood oxygen. Timepoint: pre-bronchoscopy and 1 hour after bronchoscopy. Method of measurement: pulseoxymeter.	—

Measure

Time frame

Vital sign. Timepoint: pre-bronchoscopy and 1 hour after bronchoscopy. Method of measurement: termometer,choronometer,sphygmanometer.;Cough. Timepoint: pre-bronchoscopy and 1 hour after bronchoscopy. Method of measurement: numboring score from 1 to 10.;Spirometery. Timepoint: pre-bronchoscopy and 1 hour after bronchoscopy. Method of measurement: spirometer.;Saturaton of blood oxygen. Timepoint: pre-bronchoscopy and 1 hour after bronchoscopy. Method of measurement: pulseoxymeter.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Seyedmehdi Hashemibajgani

kerman University of Medical Science

kmu_research@yahoo.com+98 34 3121 5600

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026