Efficacy of Oral Amiodarone in atrial fibrillation after open heart surgery

Efficacy of Oral Amiodarone Administration on Prevention of Cardiac Arrhythmia Following Open Heart Surgery, aRandomized Clinical trial Study

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20151109024975N8

Enrollment

400

Registered

2018-07-07

Start date

2016-04-20

Completion date

Unknown

Last updated

2018-09-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Arrhythmia after open heart surgery.

Interventions

Intervention 1: Control group: Patients in the control group received placebo (vitamin B1). The frequency and duration of placebo in the control group were similar to the oral administration of amioda

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Age over 18 years Candidate for open heart surgery Preoperative sinus rhythm Normal function of liver, renal system , pulmonary system and thyroid

Exclusion criteria

Exclusion criteria: History of atrial and ventricular arrhythmia and cardiac blocks with any degree before surgery Patient's need for Pace Anti-arrhythmic therapy before surgery The history of thyroid and lung and renal disease and hepatitis Age over 80 years Pregnant patients Allergy to Amiodarone

Design outcomes

Primary

Measure	Time frame
Prevention of various types of arrhythmias after open heart surgery. Timepoint: Duration of hospitalization. Method of measurement: monitoring.	—

Secondary

Measure	Time frame
Duration of admission to ICU. Timepoint: Duration of hospitalization. Method of measurement: Monitoring and file.;Duration of hospitalization. Timepoint: Duration of hospitalization. Method of measurement: Monitoring and file.;Side effects of amiodarone. Timepoint: Duration of hospitalization. Method of measurement: Monitoring and file.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactGohar Eslami

Sari University of Medical Sciences

g.eslami@mazums.ac.ir+98 11 3354 3695

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026