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Ascorbic acid in contrast-induced nephropathy

Ascorbic acid in preventing contrast-induced nephropathy in patients undergoing angiography : Double blind Random clinical trial

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20151109024975N7
Enrollment
100
Registered
2018-07-05
Start date
2018-06-20
Completion date
Unknown
Last updated
2018-09-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute coronary syndrome. Acute coronary thrombosis not resulting in myocardial infarction

Interventions

Intervention 1: Intervention group: 3 grams of oral vitamin C ( Dr Abidi Manufacturing) before angiography and 2 grams afterwards, and then daily for 1 gram during 5 days. Each patient receive 10 gram

Sponsors

Mazandaran University of Medical sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 85 Years

Inclusion criteria

Inclusion criteria: patients undergoing angiography and contrast media Contrast nephropathy score above 5 Age between 18-85

Exclusion criteria

Exclusion criteria: End stage Renal disease patients Contrast usage 1 week before and 72 hours after study Coadministration of nephrotoxic drug Vitamin C usage during last 1 week

Design outcomes

Primary

MeasureTime frame
Nephropathy. Timepoint: 5 days. Method of measurement: creatine.

Secondary

MeasureTime frame
????????. Timepoint: 1 week. Method of measurement: creatine.;Dialysis. Timepoint: 10 days. Method of measurement: Creatinin.;Mortality. Timepoint: 2 weeks. Method of measurement: patients follow up.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactGohar Eslami

Mazandaran University of Medical Sciences

Dr.gohar.eslami@gmail.com+98 331108906

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026