Acute coronary syndrome. Acute coronary thrombosis not resulting in myocardial infarction
Conditions
Interventions
Intervention 1: Intervention group: A dose of 0.5 g / kg of glutamine powder is administered orally once a day during the ICU for patients. Intervention 2: Control group: Patients in the control group
Sponsors
Sari University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Age over 18 years Candidate for open heart surgery Preoperative sinus rhythm Normal function of liver, renal system, pulmonary system and thyroid
Exclusion criteria
Exclusion criteria: Emergency patients Serious water and electrolyte disorders Unwillingness to co-operate with the patient History of chronic lung, liver, kidney and thyroid diseases and heart failure Age over 80 years Pregnant and lactating women Patients who are hypersensitive to glutamine or who are banned in any way by their administration of glutamine Total Bilirubin more than 10 mg / dL Creatinine clearance less than 30 ml / min Absolute Absence of Intestinal Feeding
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Myocardial injury after open heart surgery. Timepoint: The day before the surgery (before the intervention) and the first and second days after surgery. Method of measurement: SOFA score. | — |
Secondary
| Measure | Time frame |
|---|---|
| Duration of admission to ICU. Timepoint: Duration of admission. Method of measurement: Patients follow up.;Duration of hospitalization. Timepoint: Duration of admission. Method of measurement: Patients follow up.;Mortality. Timepoint: Duration of admission. Method of measurement: Patients follow up. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactGohar Eslami
Sari University of Medical Sciences
Outcome results
None listed