Degree 2 burn wounds. Burn of second degree, body region unspecified
Conditions
Interventions
Intervention 1: In the intervention group burns area are dressing with amniotic membrane. Intervention 2: In the control group burns area are dressing with gauze soaked with silver sulfadiazine ointm
Treatment - Other
In the intervention group burns area are dressing with amniotic membrane
In the control group burns area are dressing with gauze soaked with silver sulfadiazine ointment.
Sponsors
Zanjan Universiy of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: all patients wit; superficial thermal burns grade 2 less than 20% and no burns isolated to the head and neck; lack of burn areas genitalia; stable vital signs; no history of psychiatric disorders in patients with burns; the absence of drug and psychotropic; smoking, no history of heart, kidney and liver problems; no diabetes; no history of malnutrition; not taking corticosteroids or drugs that suppress the immune system; lack of burns inhalation; no history for sulfonamides toxicity; no previous burns in the recent burn site; no evidence of infection in burns and age over 18 years in patients presenting to the emergency department or clinic. Exclusion criteria: allergic reaction to silver sulfadiazine ointment; side effects or sensitivity to amniotic membrane dressing; requirement to wound debridement in the operating room.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Epithelializasion. Timepoint: Seven days, 14 days and 30 days after intervention (dressing with amniotic membrane). Method of measurement: Based on the physical examination.;Wound infection. Timepoint: Daily visits during hospitalization and based on clinical evidence and cultivation of bending if positive clinical evidence (fever, discharge and cellulite). Method of measurement: Clinical descriptions of daily visits.;Analgesia Consumption. Timepoint: Daily during admission. Method of measurement: Medical records.;Frequency of dressing exchange. Timepoint: From first until 30th day of the study. Method of measurement: The number of dressing exchange. | — |
Secondary
| Measure | Time frame |
|---|---|
| Wound scar. Timepoint: 30 days after the intervenion. Method of measurement: Physical examination (0 = no scar; 1 = mild ; 2 = moderate ; 3 = severe.;Pain. Timepoint: The seventh day after the intervention (dressing with amniotic membrane or silver sulfadiazine ointment). Method of measurement: Visual Analogue Scale. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Mehran Salehian
Zanjan Universiy of Medical Sciences
Outcome results
None listed