Post operative cognitive disorders. Mental and behavioural disorders due to use of sedatives or hypnotics
Conditions
Interventions
Intervention 1: Intervention group1: 1000 mg Passiflora Incarnata orally one hour before operation in single dose, Natiris company. Intervention 2: Intervention group2: 6 mg Melatonin orally one hour
Prevention
Intervention group1: 1000 mg Passiflora Incarnata orally one hour before operation in single dose, Natiris company
Intervention group2: 6 mg Melatonin orally one hour before surgery one hour before operation in single dose, USA Pharmavite company (Nature Made)
Sponsors
Vice Chancellor of Research & Technology, Iran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
20 Years to 60 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: American Society of Anesthesiologists(ASA) 1&2 ; age range of 20-60; minor to moderate surgery under general anesthesia Exclusion criteria: Age lower than 20 and higher than 60; diabetic patients; hypertension; depression & anti depressant drug consumption; pregnant & Lactating women; seizure & anti-convulsive drug consumption
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Post operative cognitive disorders. Timepoint: Before intervention, one hour after intervention, discharge time from recovery room. Method of measurement: Digit Symbol Substitutional Test. | — |
Secondary
| Measure | Time frame |
|---|---|
| Preoperative sedation score. Timepoint: One hour after intervention. Method of measurement: Ramsey sedation score. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSeyedeh Somayeh Seyed Alizadeh Ganji
Iran University of Medical Science
Outcome results
None listed