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"Effect of Phenylephrine in treatment of Hypotension"; "Effect of Ephedrine in treatment of Hypotension"

Comparison of the effect of Phenylephrine and Ephedrine in treatment of Spinal Anesthesia induced Hypotension in pregnant women candidate for Cesarean section

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20151107024909N8
Enrollment
62
Registered
2019-06-16
Start date
2019-01-21
Completion date
Unknown
Last updated
2019-08-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Decreased blood pressure following spinal anesthesia.

Interventions

Intervention 1: First intervention group: Phenylephrine receiving 100 microgram Bolus. Repeat this dose if needed. Intervention 2: Second Intervention group: Ephedrine receiving 10 milligram bolous. R

Sponsors

Iran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 35 Years

Inclusion criteria

Inclusion criteria: Higher than 36 weeks of gestational age Elective cesarean section under spinal anesthesia Pregnant women are healthy and uncomplicated with class ASA 1

Exclusion criteria

Exclusion criteria: Emergency Caesarean section High-risk pregnancies Spinal anesthesia is contraindicated

Design outcomes

Primary

MeasureTime frame
Blood pressure. Timepoint: Mean 3 times the blood pressure measurement before the procedure and then measuring the blood pressure at intervals of 3 minutes after the spinal anesthesia until the birth of the baby, and then every 5 minutes. Method of measurement: Automatic non-invasive blood pressure measurement device.;Heart rate. Timepoint: It is instantaneously observed and recorded simultaneously with blood pressure recordings. Method of measurement: Based on the electrocardiographs attached to the patient and observed on the monitor.

Secondary

MeasureTime frame
PH newborn. Timepoint: Maximum in one minute after leaving the uterus. Method of measurement: Blood gas analyzer.;Baby Apgar score. Timepoint: In the 1st and 5th minutes of birth. Method of measurement: Based on Apgar Score Table.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFaranak Rokhtabnak

Iran University of Medical Sciences

rolhtabnak.f@iums.ac.ir+98 21 8894 6267

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026