Cis atracurium and Tourniquet

Comparison of onset, duration and recovery time of neuromuscular blockage of Cis atracurium administration before and after inflation of Tourniquet on upper limb: Randomized clinical trial.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20151107024909N11

Enrollment

Registered

2021-10-09

Start date

2021-09-23

Completion date

Unknown

Last updated

2023-02-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cis atracurium.

Interventions

Intervention 1: Intervention group: The night before the operation, if there are conditions for inclusion in the study based on inclusion and exclusion criteria, regarding the study and actions taken

Eligibility

Sex/Gender

All

Age

20 Years to 65 Years

Inclusion criteria

Inclusion criteria: Operation is elective Operation needs general anesthesia Body mass index is between 18 -30 Age is between 20 - 60 years

Exclusion criteria

Exclusion criteria: History of liver disease History of kidney disease History of severe cardiopulmonary disease History of known neuromuscular disease such as: Guillain- Barre syndrome, Myasthenia gravis, Organophosphate and Anticholinesterase intoxication, multiple sclerosis disease and history of any musculoskeletal weakness in limbs Usage of drugs such as: Aminoglycosides, Polymyxin, Lincomycin, Clindamycin, Tetracycline, Calcium, Magnesium, Lithium, Verapamil, Amlodipine, Anti epileptic drugs, Furosemide, Dantrolene, Azathioprine, Steroid and Tamoxifen History of any vascular disease such as: Venous and arterial emboli, any impairment in circulation of limbs, Hemodialysis and history of any surgery on vessels of limbs. Sickle cell anemia Acidosis Infection in limbs Fracture in limbs Tumor in limbs Any increase in intracranial pressure Addicted patient Surgery on limbs that were examined If neuromuscular monitoring is necessary during operation

Design outcomes

Primary

Measure	Time frame
Onset time of complete neuromuscular blockage. Timepoint: From administration of Cis atracurium until complete neuromuscular blockage. Method of measurement: With Chronometer.;Complete neuromuscular block duration. Timepoint: The time between complete neuromuscular block until onset of recovery. Method of measurement: With Chronometer.;The time of neuromuscular block recovery. Timepoint: The time between onset of recovery until complete recovery of neuromuscular block. Method of measurement: With Chronometer.	—

Measure

Time frame

Onset time of complete neuromuscular blockage. Timepoint: From administration of Cis atracurium until complete neuromuscular blockage. Method of measurement: With Chronometer.;Complete neuromuscular block duration. Timepoint: The time between complete neuromuscular block until onset of recovery. Method of measurement: With Chronometer.;The time of neuromuscular block recovery. Timepoint: The time between onset of recovery until complete recovery of neuromuscular block. Method of measurement: With Chronometer.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactSaeed aghakhani

Iran University of Medical Sciences

aghakhani.said@gmail.com+98 21 8894 6267

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026