Condition 1: acne. Condition 2: Atrophic scar. Acne vulgaris Scar conditions and fibrosis of skin
Conditions
Interventions
Intervention 1: Microneedeling, 4 times, 3 weeks apart. Intervention 2: Microneedeling and topical platelet-rich plasma (PRP) , 4 times, 3 weeks apart. Intervention 3: Co2 fractional laser, 4 times,
Treatment - Other
Microneedeling, 4 times, 3 weeks apart
Microneedeling and topical platelet-rich plasma (PRP) , 4 times, 3 weeks apart
Co2 fractional laser, 4 times, 3 weeks apart
Sponsors
Research DepartmentIran of Univercity of Medical Science
Eligibility
Sex/Gender
All
Age
20 Years to 50 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Patient with atrophic acne scars; Ages 20 to 50 years old Exclusion criteria: Active acne; Patients with platelet dysfunction, sever thrombocytopenia (less than 50,000); Any hemodynamic instability or chronic diseases (such as diabetes, chronic infections, blood dyscrasia ); Local inflammatory skin disorder or active herpes infection at the site of the procedure; Taking an anticoagulant or NSAID within 48 hours before the procedure; Corticosteroid injection at the treatment site during 1 month; Use of systemic corticosteroids within 2 weeks; Fever or recent illness; Cancer, particularly bone or blood; Hemoglobin level less than 10 grams per deciliter
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Response to treatment. Timepoint: Three weeks after each session and 3 months after the last session. Method of measurement: By a physician, according to the measure of the severity of acne scar goodman and high quality photography by visioface device.;Patient satisfaction rate of response to treatment. Timepoint: Three weeks after each session and 3 months after the last session. Method of measurement: Questionnaire(percentage). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactFatemeh Zahra Mohammadi
Rasul Akram Hospital
Outcome results
None listed