Postrhinoplasty periorbital edema and ecchymosis. Other medical procedures as the cause of abnormal reaction of the patient,or of later complication,without mention of misadventure at the time of the procedure
Conditions
Interventions
Intervention 1: Group 1(Dexamethasone intervention): IV injection a dose of 8mg,one hour before surgery and then 3 doses per 8 hours after surgery. Intervention 2: Group 2(tranexamic acid):IV injectio
Treatment - Drugs
Group 1(Dexamethasone intervention): IV injection a dose of 8mg,one hour before surgery and then 3 doses per 8 hours after surgery
Group 2(tranexamic acid):IV injection a dose of 10 mg/kg,one hour before and 3 doses every 8 hours after surgery.
Group 3(Dexamethasone and tranexamic acid intervention):IV injection a dose of 8 mg dexamethasone and a dose of 15 mg/kg tranexamic acid,one hour before surgery and then 3 doses of both drugs per 8
Sponsors
Vice Chancellor for Research of BABOL UNIVERSITY OF MEDICAL SCIENCES
Eligibility
Sex/Gender
All
Age
18 Years to 39 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria:candidates aged 18-39 for rhinoplasty ;similar nasal deformity ;need for hump removal and lateral and medial osteotomy ;ASA=1 Exclusion criteria:history of peptic ulcer;diabetes mellitus;cardiovascular disease;thromboembolism;pregnancy;renal failure;seizure;anticoagulants;herpes simplex;tuberculosis;glaucoma;active infection;psychiatric problems;coagulation disorders;sensitivity to corticostroids and tranexamic acid ;need for septoplasty
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Periorbital edema. Timepoint: 1,3,7 days after rhinoplasty. Method of measurement: GURLEK standard scales.;Periorbital ecchymosis. Timepoint: 1,3,7 days after rhinoplasty. Method of measurement: GURLEK standard scales. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactHosein Ghanepur
BABOL UNIVERSITY OF MEDICAL SCIENCES
Outcome results
None listed